Szlávicz, Eszter ORCID: https://orcid.org/0000-0002-1083-0994, Szabó, Ákos ORCID: https://orcid.org/0000-0003-2386-4525, Kinyó, Ágnes ORCID: https://orcid.org/0000-0002-9827-2690, Szeiffert, Anita, Bancsok, Tamas, Brodszky, Valentin ORCID: https://orcid.org/0000-0002-6095-2295, Gyulai, Rolland Péter ORCID: https://orcid.org/0000-0002-3286-8846 and Rencz, Fanni ORCID: https://orcid.org/0000-0001-9674-620X (2024) Content validity of the EQ-5D-5L with skin irritation and self-confidence bolt-ons in patients with atopic dermatitis : a qualitative think-aloud study. Quality of Life Research, 33 (1). pp. 101-111. DOI 10.1007/s11136-023-03519-6
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Official URL: https://doi.org/10.1007/s11136-023-03519-6
Abstract
Objectives Two bolt-on dimensions (skin irritation, self-confidence) have been developed for the EQ-5D-5L to improve its content validity and responsiveness in psoriasis. However, the two bolt-ons are not strictly psoriasis-specific and are potentially relevant in other skin conditions. This study aims to explore the content validity of the EQ-5D-5L with two bolt-ons in patients with atopic dermatitis (AD). Methods In 2021–2022, qualitative, semi-structured interviews were conducted with 20 adult AD patients at a university dermatology clinic in Hungary. We aimed for a heterogeneous sample in terms of age, gender, education and disease severity. Patients completed the EQ-5D-5L with two bolt-ons using a think-aloud protocol. Probing questions were posed to investigate item relevance, potential conceptual overlaps, missing concepts and the appropriateness of the recall period. Interview transcripts were subjected to thematic analysis. Results The EQ-5D-5L with the two bolt-ons covered the most important aspects of health-related quality of life in AD patients. Most patients found both the skin irritation and self-confidence bolt-ons relevant. Fifteen potential missing concepts were identified, but only two (social relationships, judgement by others) were identified by more than one patient. A smaller conceptual overlap was found between the skin irritation and pain/discomfort dimensions in 7 patients (35%). Half the patients expressed a preference for a recall period of 1 week rather than of ‘today’. Conclusions The EQ-5D-5L with skin irritation and self-confidence bolt-ons showed good relevance, comprehensiveness and comprehensibility in patients with AD. However, in terms of comprehensiveness, social relationships and judgement by others (stigma) may be missing from the questionnaire.
Item Type: | Article |
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Uncontrolled Keywords: | EQ-5D-5L ; Atopic dermatitis ; Skin irritation ; Self-confidence ; Bolt-on ; Content validity |
Divisions: | Institute of Social and Political Sciences |
Subjects: | Social welfare, insurance, health care |
Funders: | University of Pécs, New National Excellence Programme of the Ministry for Culture and Innovation, János Bolyai Research Scholarship of the Hungarian Academy of Sciences |
Projects: | Open access funding, ÚNKP-22-3-II-SE-5, BO/00304/21, ÚNKP-22-5-CORVINUS-4 |
DOI: | 10.1007/s11136-023-03519-6 |
ID Code: | 10752 |
Deposited By: | MTMT SWORD |
Deposited On: | 15 Jan 2025 13:15 |
Last Modified: | 15 Jan 2025 13:15 |
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