Subjective well‑being in patients with pemphigus: a path analysis

Mitev, Ariel Zoltán, Rencz, Fanni, Tamási, Béla, Hajdu, Krisztina, Péntek, Márta, Gulácsi, László, Szegedi, Andrea, Bata‑Csörgő, Zsuzsanna, Kinyó, Ágnes, Sárdy, Miklós and Brodszky, Valentin (2019) Subjective well‑being in patients with pemphigus: a path analysis. The European Journal of Health Economics, 2019 (20). S101-S107. DOI

PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader

Official URL:

A nyílt hozzáférést az EISZ és a kiadó között létrejött "Read and Publish" szerződés biztosította. Open access was provided "Read and Publish" contract between EIS and the publisher.


Background Pemphigus is a chronic autoimmune blistering disease of the skin and mucosa severely impairing patients’ health-related quality of life (HRQoL). To date, no studies have measured subjective well-being in terms of life satisfaction in pemphigus. Our main objective was to evaluate satisfaction with life in patients with pemphigus, and to analyse its relationship with clinical severity and HRQoL. Methods A cross-sectional survey was carried out enrolling 77 patients with pemphigus. Subjective well-being was measured using the Satisfaction with Life Scale (SWLS). HRQoL was assessed by the Dermatology Life Quality Index (DLQI) and EQ-5D-5L. Disease severity was measured by Autoimmune Bullous Skin Disorder Intensity Score (ABSIS). Results Mean ABSIS, DLQI, EQ-5D-5L and SWLS scores of patients were 11.7 (SD 17.3), 5.4 (6.8), 0.84 (0.22) and 4.76 (SD 1.52), respectively. The proportion of patients indicating extreme dissatisfaction, dissatisfaction, slightly below average in life satisfaction, average satisfaction, high satisfaction and very high satisfaction with life was 6 (7.8%), 5 (6.5%), 14 (18.2%), 16 (20.8%), 21 (27.3%) and 15 (19.5%), respectively. Life satisfaction was independent from age, gender, level of education and type of disease. A path analysis revealed that there was no direct relationship between ABSIS and SWLS (beta=−0.09; p=0.428); however, the following indirect path was confrmed: ABSIS→DLQI→EQ-5D-5L→SWLS. Conclusions Disease severity and HRQoL measures regularly used to assess patients’ health status may be complemented with a measure of subjective well-being, such as SWLS, to achieve a more holistic assessment of patients’ lives and optimise pemphigus care.

Item Type:Article
Uncontrolled Keywords:Pemphigus vulgaris · Pemphigus foliaceus, path analysis, health-related quality of life, satisfaction with life, subjective well-being
JEL classification:I10 - Health: General
Social welfare, insurance, health care
ID Code:5318
Deposited By: Veronika Vitéz
Deposited On:04 Apr 2020 16:26
Last Modified:04 Apr 2020 16:26

Repository Staff Only: item control page


Downloads per month over past year

View more statistics