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Parallel Valuation of the EQ-5D-3L and EQ-5D-5L by Time Trade-Offin Hungary

Rencz, Fanni and Brodszky, Valentin and Gulácsi, László and Golicki, Dominik and Ruzsa, Gábor and Pickard, A. Simon and Law, Ernest H. and Péntek, Márta (2020) Parallel Valuation of the EQ-5D-3L and EQ-5D-5L by Time Trade-Offin Hungary. Value in Health, 23 (9). pp. 1235-1245. DOI https://doi.org/10.1016/j.jval.2020.03.019

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Official URL: https://doi.org/10.1016/j.jval.2020.03.019

A nyílt hozzáférést az EISZ és a kiadó között létrejött "Read and Publish" szerződés biztosította. Open access was provided "Read and Publish" contract between EIS and the publisher.

Abstract

Objectives The wording of the Hungarian EQ-5D-3L and EQ-5D-5L descriptive systems differ a great deal. This study aimed to (1) develop EQ-5D-3L and EQ-5D-5L value sets for Hungary from a common sample, and (2) compare how level wording affected valuations. Methods In 2018 to 2019, 1000 respondents, representative of the Hungarian general population, completed composite time trade-off tasks. Pooled heteroscedastic Tobit models were used to estimate value sets. Value set characteristics, single-level transition utilities from adjacent corner health states, and mean transition utilities for all possible health states were compared between the EQ-5D-3L and EQ-5D-5L. Results Health utilities ranged from -0.865 to 1 for the EQ-5D-3L and -0.848 to 1 for the EQ-5D-5L. The relative importance of the 5 EQ-5D-5L dimensions was as follows: mobility, pain/discomfort, self-care, anxiety/depression, and usual activities. A similar preference ranking was observed for the EQ-5D-3L with self-care being more important than pain/discomfort. The EQ-5D-5L demonstrated lower ceiling effects (range of utilities for the mildest states: 0.900-0.958 [3L] vs 0.955-0.965 [5L]) and better consistency of mean transition utilities across the range of scale. Changing “confined to bed” (3L) to “unable to walk” (5L) had a large positive impact on utilities. Smaller changes with more negative wording in the other dimensions (eg, “very much anxious/feeling down a lot” [3L] vs “extremely anxious/depressed” [5L]) had a modest negative impact on utilities. Conclusion This study developed value sets of the EQ-5D-3L and EQ-5D-5L for Hungary. Our findings contribute to the understanding of how the wording of descriptive systems affects the estimates of utilities.

Item Type:Article
Uncontrolled Keywords:EQ-5D, value set, composite time trade-off, QALY, Europe
Subjects:Economics
Social welfare, insurance, health care
DOI:https://doi.org/10.1016/j.jval.2020.03.019
ID Code:6122
Deposited By: Veronika Vitéz
Deposited On:01 Dec 2020 13:59
Last Modified:01 Dec 2020 13:59

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